cancer symptoms

Can Cats Get Breast Cancer? Learn About Mammary Tumors in Cats

What is a mammary tumor (breast cancer)?

A mammary tumor develops as a result of abnormal replication of the cells that make up the breast tissue. Mammary tumors can be benign (non-cancerous) or malignant (cancerous). These two forms of the disease have different diagnostics, treatments, management, and prognosis. In cats, the vast majority of mammary tumors are malignant.

There are several different types of mammary tumors, with carcinomas being the most common. Carcinomas often arise from the tubules of the mammary glands, or other cells found in the mammary chain.

There are several other kinds of cancers that can affect the mammary glands, including osteosarcomas.

What causes this cancer?

The exact causes for the development of mammary tumors in cats are not fully understood. However, exposure to the female reproductive hormones, estrogen and progesterone, increases the risk for mammary cancers in cats. It is hypothesized that under the influence of hormones, the cells of the mammary gland enlarge, progress to a pre-cancerous state, and continue to grow until they transform into a carcinoma.

The incidence of these tumors is related to hormone status, specifically whether a cat is intact or has had an ovariohysterectomy (i.e., has been spayed). Sexually intact cats have a 7-fold increased risk for mammary tumors compared to spayed cats. Early spaying helps to prevent the development of these tumors. Cats that are spayed before 6 months of age have only a 9% percent risk of developing mammary tumors, whereas the risk increases to 14% in cats spayed between 7 and 12 months. Male cats rarely develop mammary tumors.

Age and breed also play a role in tumor development. Mammary cancers are seen mainly in middle-aged to older cats (around 10 years of age). Siamese cats appear to be predisposed and are typically younger when diagnosed. Obesity may play a role in tumor development as well.

What are the signs that my cat has this type of tumor?

The most common clinical sign of a mammary tumor is one (or more) palpable masses (nodules) underneath the skin of the abdomen. They may be next to or within the nipple and follow along the mammary chain. The size of the mass(es) and their appearance may vary, but they are usually firm and nodular. Occasionally the skin over the mass may ulcerate (open) and bleed, and the affected area may feel warm to the touch and become painful. Your cat may tend to lick and groom the area excessively, and a strong odor can result as the exposed tissue becomes infected.

If the tumor has metastasized (spread to other areas of the body), other signs may become evident. Your cat may generally feel unwell, eat less, become lethargic, and lose weight. If the lungs are involved, your cat may have problems breathing or develop a cough.

Multiple tumors are common at the time of diagnosis.

How is this type of tumor diagnosed?

These tumors are typically found as either singular or multiple nodules along your cat’s abdomen during a physical exam. Other procedures are then performed to determine the type of tumor and whether it is benign or malignant.

A common procedure to diagnose this tumor is a fine needle aspiration (FNA). FNA involves taking a small needle with a syringe and suctioning a sample of cells directly from the tumor and placing them on a microscope slide. A veterinary pathologist then examines the slide under a microscope.

In some cases, results from FNA may not be entirely clear and removal of the entire tumor may be necessary. Pieces of the tumor are then examined by a veterinary pathologist under a microscope. This is called histopathology. Histopathology is not only helpful to make a diagnosis but can indicate whether it is benign or malignant, and therefore how the tumor is likely to behave.

Given the risk of metastasis (spread to other areas of the body) with malignant mammary tumors, your veterinarian may also recommend staging (searching for potential spread to other locations in the body). This may include bloodwork, urinalysis, X-rays of the lungs, and possibly an abdominal ultrasound. Lymph nodes associated with the mammary glands may be sampled by FNA even if they seem normal.

How does this cancer typically progress?

The way this cancer progresses is entirely dependent on the type and size of the tumor(s), and whether metastasis has occurred. Larger tumors (greater than 2 cm) and those with evidence of spread have a poor prognosis. If the histopathology report shows tumor cells invading the local blood vessels, this also carries a poor prognosis. Detecting and treating these tumors when they are small and prior to metastasis provides your cat with the best chance of long-term control. Tumors smaller than 2 cm carry the best prognosis.

What are the treatments for this type of tumor?

Surgery is by far the best treatment for cats with mammary tumors. Depending on whether there is a single mass present, or several masses a single chain mastectomy (removal of one side of the breast tissue) or double chain mastectomy (removal of both sides, with each mastectomy performed at a different time) will be performed. Depending on the tumor size and other factors, chemotherapy is typically pursued afterward, especially given the high metastatic rate in these tumors.


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cat health

10 Warning Signs of Cancer in Cats and Dogs

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If cancer is detected early it can be treated more effectively, so it’s important to check your dogs & cats regularly for these 10 warning signs of cancer as recommended by the Veterinary Cancer Society.

If your dog or cat has any of these early warning signs of cancer, you should take them to your veterinarian as soon as possible for a more thorough and complete examination. In addition, you should keep your pet away from environmental toxins such as lawn fertilizers and surface & rug cleaners that have warning labels relative to children and pets, due to a potential link between environmental toxins and cancer.

01 / Swollen lymph nodes

The lymph nodes are glands that are located throughout the body. They are most easily detected behind the jaw or behind the knee. When these lymph nodes are enlarged, it can suggest a common form of cancer called lymphoma. A biopsy or cytology of the enlarged lymph nodes can aid in the diagnosis.

02 / Enlarging (or changing) lump

Any lump on a pet that is rapidly growing or changing in texture or shape should have a biopsy.

03 / Abdominal distension

When the stomach becomes rapidly enlarged, this may suggest a mass or tumor in the abdomen, or it may indicate some bleeding that is occurring in this area. A radiograph or an ultrasound of the abdomen can aid in diagnosing.

04 / Chronic weight loss

When a pet is losing weight and you have not put your pet on a diet, you should have your pet checked. This sign is not a definitive diagnostic for cancer but can indicate that something is wrong.

05 / Chronic vomiting or diarrhea

Vomiting or diarrhea should always prompt further investigation. Often tumors of the gastrointestinal tract can cause chronic vomiting and/or diarrhea. Radiographs, ultrasound examinations, and endoscopy are useful diagnostic tools when these symptoms present themselves.

06 / Oral Odor

Oral tumors can occur in pets and can cause a pet to change its food preference (i.e. from hard to soft foods) or cause a pet to change the manner in which they chew their food. Many times a foul odor can be detected in pets with oral tumors. A thorough oral examination with radiographs or CT scans, necessitating sedation, is often necessary to determine the cause of the problem.

07 / Unexplainable bleeding

Although bleeding disorders do occur in pets, they usually are discovered while pets are young. If unexplained bleeding starts when a pet is old, a thorough search by your veterinarian should be undertaken.

08 / Cough

There are many causes of a cough in dogs and cats. However, dry, non-productive coughing in an older pet should prompt chest radiographs to be taken, as this type of cough is the most common sign of lung cancer.

09 / Lameness

Unexplained lameness, especially in large or giant breed dogs, is a very common sign of bone cancer. Radiographs of the affected area are useful for detecting cancer of the bone.

10 / Straining to urinate

Straining to urinate and blood in the urine usually indicate a common urinary tract infection; if the straining and bleeding are not rapidly controlled with antibiotics or are recurrent, cancer of the bladder may be the underlying cause. Cystoscopy or other techniques that allow a veterinarian to take a biopsy of the bladder are useful and sometimes necessary to establish a definitive diagnosis in these cases.


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